Sentinel lymph nodes

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Contrast enhanced ultrasound of sentinel lymph nodes

Sentinel lymph nodes are the first lymph nodes in the region that receive lymphatic drainage from a primary tumor. The detection or exclusion of sentinel lymph node micrometastases is critical in the staging of cancer, especially breast cancer and melanoma because it directly affects patient's prognosis and surgical management. Currently, intraoperative sentinel lymph node biopsies using blue d...

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Pathology of sentinel lymph nodes for melanoma.

As a concept sentinel lymph node biopsy seems attractive in that it attempts to identify the first lymph node, rather than the nearest node, draining a particular anatomic area where a tumour has arisen. Pathological assessment can then indicate whether metastases are present and the procedure is either a strong prognostic indicator or possibly therapeutic in itself. These comments apply to any...

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Novel Biomarkers Aim at Detecting Metastatic Sentinel Lymph Nodes in Breast Cancer

Background: Intra-operative molecular diagnostic assays are currently used for the detection of lymph node metastases. The objective of this study was to find new biomarkers to improve diagnostic accuracy in the detection of metastatic axillary lymph nodes in breast cancer patients. Methods: We applied an absolute quantitative real-time RT-PCR to quantitate the expression of CK19, KLK11, and CL...

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intra-operative assessment of sentinel lymph nodes in breast cancer

lymph node status remains an important prognostic indicator for survival in breast cancer. sentinel lymph node biopsy has become the standard method of assessment of clinically node negative breast cancers. economic implications as well as patient related factors have lead to the development a number of intra-operative techniques. review of the emerging trends in the last 4 years show that alth...

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Breast cancer patients with micrometastases in sentinel lymph nodes: differences considering additional metastatic lymph nodes.

AIMS Characterization of breast cancer patients with micrometastases in sentinel lymph node (SLN) and establish differences between micrometastatic breast cancers with additional metastatic lymph nodes (LNS) versus no other lymph node invasion. METHODS Analysis of 30 breast cancers, N1mi or pN0(i+), diagnosed and treated in our department from July 2000 to July 2008. RESULTS Micrometastases...

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ژورنال

عنوان ژورنال: Cancer

سال: 2003

ISSN: 0008-543X,1097-0142

DOI: 10.1002/cncr.11811